SELANK

An anxiolytic peptide without sedation

Focus, Mood, & SleepSingle

Pricing & Sizes

Pricing
10mg vial
$40
Solution — 4mL metered bottle
$50
Bulk pricing: 2-3 vials −5%4-6 vials −10%7-9 vials −15%10+ vials −20%

Vials ship sealed and lyophilized. Free shipping on every order, no minimum. Every batch ships with its lab report. Reports come from third-party labs including Janoshik, Freedom Diagnostics and Chromate, most verifiable through the lab's own public portal. Ask and we will send the report for your batch.

Lab report on file. Current batch tested by Janoshik — HPLC. Verifiable through the lab's public portal; ask and we will send it.

Reconstitution — bacteriostatic water: 10mg vial reconstituted at 2mL gives 5mg/mL; Solution — 10mg in 4mL bacteriostatic saline = 2.5mg/mL. These are concentrations, calculated from vial content and diluent volume. They describe the solution, not a dose.

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In Plain English

Most anti-anxiety drugs work by broadly damping the nervous system, which is why they cause drowsiness and fog. Selank appears to work more selectively — adjusting the balance of the brain’s own calming and mood chemistry rather than sedating it wholesale. The reported result is reduced anxiety while staying clear-headed, which is why it pairs well with an activating compound like Semax.

What people use it for. Anxiety, stress, and mental steadiness — particularly by people who want the calming effect without feeling sedated or foggy. It is very commonly paired with Semax.

What to know before you buy. The interesting claim here is not that it works but how it is reported to work — without the tolerance, dependence or next-day fog that benzodiazepines produce. That is a meaningful distinction if it holds. The evidence is real human clinical data, but almost all of it is Russian and much of it lacks the detail Western reviewers expect. Taken through the nose.

What It's Studied For

Research areaWhat that rests on
Anxiety and stressRussian clinical research in generalised anxiety and adjustment disorders
Calm without sedationThe distinguishing claim — anxiolytic effect reported without drowsiness, tolerance or withdrawal
Clearer thinking under stressSome studies report attentional and cognitive improvement alongside anxiety reduction
Pairs with SemaxComplementary profiles; the most common way either is used

The left column lists the research areas this compound is investigated in; the right column states what that rests on. These are published research findings, not proven outcomes or treatment claims, and nothing here is a recommendation. Sold for laboratory research use only.

At a Glance

Class
Heptapeptide; a synthetic analogue of the immunomodulatory peptide tuftsin
Mechanism
Modulates GABAergic and serotonergic signalling; also affects BDNF expression and enkephalin degradation
Origin
Institute of Molecular Genetics, Russian Academy of Sciences
Distinguishing claim
Anxiolytic activity reported without the sedation, tolerance or withdrawal profile associated with benzodiazepines
Regulatory (US)
Not FDA-approved. Not on the July 2026 PCAC agenda — status unchanged by that hearing
Route
Intranasal is the native route; oral bioavailability is essentially zero
Format
10mg vial, or prepared solution in a 4mL bottle
7amino acids
Tuftsinparent peptide
Not reviewedJuly 2026 PCAC
Intranasalnative route

Regulatory status

This compound was not on the July 2026 PCAC agenda. Its regulatory status is unchanged by that hearing, and reports about peptides being “cleared” in July 2026 do not apply to it. Treat its status as independent. Selank remains not FDA-approved and is not on the 503A bulks list. It has not been publicly confirmed as one of the five peptides queued for the expected February 2027 PCAC meeting.

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What the Research Shows

Selank’s clinical record comes primarily from Russian research on generalised anxiety disorder and adjustment disorders, including studies comparing it against benzodiazepines. Reported findings centre on anxiolytic effect without the sedation, tolerance or withdrawal pattern that limits benzodiazepine use, and some work reports cognitive and attentional improvement alongside anxiety reduction.

The limitations mirror those FDA raised for Semax at the July hearing: much of the literature is published in Russian, and study reports frequently omit dosing, route, and design detail that Western review expects. This is real human clinical data, but it is not equivalent to a Western randomised controlled trial and should not be presented as one.

Mechanistic notes

Beyond GABAergic and serotonergic modulation, Selank has been reported to influence BDNF expression and to slow the degradation of enkephalins, the body’s own opioid-like signalling peptides. Its tuftsin lineage also gives it documented immunomodulatory activity, which is a less discussed part of its profile.

The bottom line

One of the better-documented compounds in this range, with a distinctive and clinically meaningful claim: anxiety reduction without sedation. The evidence is real but geographically concentrated, and its US regulatory position is untouched by the July 2026 hearing.

Also in the Range

Also available paired with Semax. Selank alone is the option if you want the anxiolytic effect without the activating half.