Pricing & Sizes
Ships sealed and lyophilized — stable for years at room temperature, supplied as lyophilised powder. Free shipping on every order, no minimum. Every batch ships with its lab report. Reports come from third-party labs including Janoshik, Freedom Diagnostics and Chromate, most verifiable through the lab's own public portal. Ask and we will send the report for your batch.
Reconstitution — bacteriostatic water: 500mg vial reconstituted at 3mL gives 166.7mg/mL; 1000mg vial reconstituted at 5mL gives 200mg/mL. These are concentrations, calculated from vial content and diluent volume. They describe the solution, not a dose.
Email To OrderIn Plain English
NAD+ is the molecule your mitochondria use to convert food into usable energy, and it is also required for DNA repair. Levels drop measurably with age, across every species that has been looked at. That much is settled biochemistry rather than marketing, and it is the reason the molecule gets the attention it does.
What people use it for. Energy, mental clarity, recovery, and general anti-ageing. It is one of the most popular compounds in the longevity category.
What to know before you buy. The biology is well established — NAD+ is essential to how your cells make energy and to DNA repair, and tissue levels fall with age across every species studied. One reaction is reported often enough to be worth knowing about: flushing, chest tightness and nausea. The literature describes these as tracking the rate at which NAD+ enters circulation rather than the amount, and they are not immune-mediated.
What It's Studied For
| Research area | What that rests on |
|---|---|
| Cellular energy | NAD+ is essential to mitochondrial energy production — settled, textbook biology |
| DNA repair | Required by PARP enzymes for DNA repair and by sirtuins for their signalling roles |
| Replacing age-related decline | Tissue NAD+ falls substantially with age across multiple species |
| Evidence base | Whether injected NAD+ raises levels inside cells is genuinely debated. Most stronger human research is on precursors |
The left column lists the research areas this compound is investigated in; the right column states what that rests on. These are published research findings, not proven outcomes or treatment claims, and nothing here is a recommendation. Sold for laboratory research use only.
At a Glance
- Class
- Nicotinamide adenine dinucleotide — an essential coenzyme, not a drug
- Function
- Central to mitochondrial energy production, DNA repair via PARP enzymes, and sirtuin signalling
- Age decline
- Tissue NAD+ levels fall substantially with age, which is the basis for the entire supplementation category
- The open question
- Whether administered NAD+ enters cells intact, or is broken down and reassembled from precursors
- Evidence
- Strong for the biology; limited and mixed for direct NAD+ administration in humans
- Regulatory (US)
- Not FDA-approved as a drug. Not on the July 2026 PCAC agenda
- Format
- 500mg and 1000mg buffered vials
Administration note
Flushing, chest tightness and nausea are commonly reported with rapid administration of injectable NAD+. Slow administration is the standard mitigation, and it is the one practical thing worth knowing before you start. Not on the July 2026 PCAC agenda.
What the Research Supports
Well established
- NAD+ is essential to mitochondrial energy metabolism
- NAD+ is required by PARP enzymes for DNA repair and by sirtuins for their signalling functions
- Tissue NAD+ declines with age across multiple species
Not established
- That administered NAD+ meaningfully raises intracellular NAD+ in humans
- That raising NAD+ produces the anti-ageing outcomes commonly claimed for it
- That injected NAD+ raises intracellular levels more than the body's own resynthesis route
Reported subjective effects during and after IV or injectable NAD+ — and the flushing, chest tightness and nausea that frequently accompany rapid administration — are widely described. Slow administration is the standard mitigation for those effects.
The bottom line
Settled biochemistry with one open question attached. The age-related decline is real and the pathways it feeds are not in dispute. How much of an administered dose reaches the inside of a cell intact is the part still being worked out.
Also in the Range
Compare with 5-Amino-1MQ, which targets NAD+ from the other direction — blocking the enzyme that depletes it rather than supplying the molecule itself.